ClariGen & Doxycycline

SKINCARE
·
PRESCRIPTION

ClariGen & Doxycycline

Tretinoin
·
Clindamycin
·
Spironolactone
·
Doxycycline

HORMONAL ACNE
TEXTURE
TONE

One holistic protocol for stubborn acne. A triple-active topical plus a daily antibiotic that works from the inside, for inflamed, hormonal breakouts.

ClariGen topical: Tretinoin, Spironolactone and Clindamycin help unclog pores, curb excess oil and target acne-causing bacteria.
Daily doxycycline: A prescription antibiotic that reduces acne-causing bacteria and calms inflammation, helping clear active, inflamed breakouts.

HSA/FSA Eligible
Free Delivery
Consult & Care Included

30 day supply. Pause, change frequency or cancel at any time.

WHAT HAPPENS NEXT

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Doctor reviews & prescribes

ClariGen: Apply a pea-sized amount nightly to clean skin, as tolerated. On ClariGen nights, skip other retinols. Protect your skin daily with SPF.
Doxycycline: Take one capsule by mouth once daily.

Compounded medication. Not reviewed by the FDA for safety or effectiveness. Oral Doxycycline is FDA-approved as adjunctive therapy for severe acne; other uses are off-label. Price includes doctor consult fee of $20. Rx required. A licensed provider will review your information and prescribe treatment only if appropriate.

Every ingredient, intentional

What's in the formula, what it does, and why our physicians chose it.

What's in the formula, what it does,
and why our physicians chose it.

Tretinoin

Widely regarded as the gold standard for both acne and signs of aging. Tretinoin binds directly to retinoid receptors to accelerate cell turnover, decrease oil production, and signal collagen and elastin renewal.

Clindamycin

A prescription antibiotic that targets acne-causing bacteria directly at the source. Works synergistically with retinoids to help reduce inflammatory lesions and lower the risk of antibiotic resistance.

Spironolactone

Blocks the androgen receptors that drive excess oil production and hormonal breakouts. A prescription-only ingredient used off-label to help address hormonal acne at the source.

Ceramide Complex

Lipids that make up approximately 50% of the skin barrier's composition. Replenish the structural integrity of the stratum corneum when prescription actives cause barrier disruption.

Doxycycline

A prescription antibiotic that reduces acne-causing bacteria and calms inflammation. Helps clear active, inflamed breakouts and is also often prescribed for inflammatory rosacea symptoms.

How it works

Choose your treatment

Select the treatment that fits your needs and complete checkout. No waiting room, no appointment required.

Answer a few questions

Tell us about your health goals and concerns through a simple, secure questionnaire.

Physician reviews and prescribes

A board-certified physician reviews your intake and issues a prescription if clinically appropriate. You'll approve any changes your doctor suggests before your treatment is confirmed.

Access ongoing support

Message your physician anytime with questions, follow-ups, or to discuss adjustments to your treatment.

Two prescriptions for stubborn, inflamed breakouts:

ClariGen: a topical with Spironolactone, Clindamycin, and Tretinoin to unclog pores, curb excess oil, and target acne-causing bacteria
Oral Doxycycline: a daily antibiotic that reduces acne-causing bacteria and calms inflammation

They work on breakouts from two directions. Doxycycline works from the inside to calm active, inflamed breakouts, while ClariGen works on the skin to keep pores clear and curb oil where breakouts form. Doxycycline is often prescribed as a short course rather than a lasting fix on its own, so your physician will tell you when it makes sense to continue with ClariGen alone.

Most patients start noticing fewer breakouts within 6 to 8 weeks, with continued improvement over the following months. Mild dryness or irritation from Tretinoin can occur early on. That’s just part of the adjustment period, not a sign it’s not working.

No. Neither ClariGen nor Doxycycline should be used during pregnancy, and neither is recommended while breastfeeding. Tell your provider if either applies, or if you’re trying to conceive, and they’ll help you find a safer option.

Your price includes your prescription treatment, physician consultation, and ongoing care, including unlimited messaging with your doctor for questions, follow-ups, or treatment adjustments. You can also adjust your delivery frequency, pause, or cancel anytime.

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ClariGen & Doxycycline